refractory disease definition

Refractory Gastroesophageal Reflux Disease

Refractory Gastroesophageal Reflux Disease Pathophysiology Diagnosis and Management Abstract Gastroesophageal reflux disease (GERD) is one of the most commonly encountered gastrointestinal diseases

Refractory Depression Management

Definition (MSH) Marked depression appearing in the involution period and characterized by hallucinations delusions paranoia and agitation. Definition (PSY) Affective disorder marked by dysphoric mood inactivity lack of interest insomnia feelings of worthlessness diminished ability to think and thoughts of suicide.

Refractory disease in systemic lupus erythematosus

There is no definition or guidelines for refractory disease (RD) in Systemic Lupus Erythematosus (SLE). However new therapies have been tested mainly in refractory patients. The concept like the disease is complex and implies deeper knowledge on the disease pathogenesis and patients subsets.

Refractory Celiac DiseaseNORD (National Organization

Refractory celiac disease (RCD) is a complex autoimmune disorder much like the more common celiac disease but unlike celiac disease it is resistant or unresponsive to at least 12 months of treatment with a strict gluten-free diet.

Relapsed and Refractory Leukemia and Lymphoma Society

Refractory AML Most patients achieve a remission (an absence of signs and symptoms) after initial treatment for acute myeloid leukemia (AML). However some patients have residual leukemic cells in their marrow even after intensive treatment.

Outcomes in refractory diffuse large B‐cell lymphoma

Jan 22 2021 · Refractory disease resulted in poor clinical outcomes in DLBCL. However there have been discrepancies in the definition of refractory DLBCL among clinical studies due to different therapeutic strategies.

UpToDate

REFRACTORY DISEASE Definition — Refractory KD results from failure to abort the disease process and is defined as any of the following ● Persistent fever of any magnitude 24 to 36 hours after completion of initial intravenous immune globulin (IVIG) therapy

Refractory Gastroesophageal Reflux Disease

Refractory Gastroesophageal Reflux Disease Pathophysiology Diagnosis and Management Abstract Gastroesophageal reflux disease (GERD) is one of the most commonly encountered gastrointestinal diseases in clinical practice. Proton pump inhibitors (PPI) remain the cornerstone of the treatment of GERD.

Hodgkin Lymphoma Relapsed/RefractoryLRF

Hodgkin Lymphoma Relapsed/Refractory. The term "relapsed" refers to disease that reappears or grows again after a period of remission. The term "refractory" is used to describe when the lymphoma does not respond to treatment (meaning that the cancer cells continue to grow) or when the response to treatment does not last very long.

The Difference Between Relapsed Lymphoma and Refractory

Refractory Cancer "Refractory" refers to a cancer that proves resistant or does not respond to treatment. It doesn t matter whether the cancer is resistant to treatment immediately or whether it develops a resistance during treatment it is still called refractory.

Relapsed/Refractory Multiple Myeloma Disease Overview

Mar 12 2021 · Again we know that multiple myeloma is a heterogeneous disease and so even within the bone marrow you can have patchy involvement with their disease status. So I think it ll be a little bit before we start to see MRD being assessed in the relapsed/refractory

What is REFRACTORY MENTAL ILLNESS definition of

Apr 28 2013 · REFRACTORY MENTAL ILLNESS. Mental disability or disease which fails to respond to treatment remaining problematic to cure. REFRACTORY MENTAL ILLNESS " Schizophrenia is a refractory mental illness." Cite this page N. Pam M.S. "REFRACTORY MENTAL ILLNESS " in PsychologyDictionary April 28 2013 https //psychologydictionary

Refractory Gastroesophageal Reflux Disease (GERD) Symptoms

Mar 12 2018 · Gastroesophageal reflux disease (GERD) is a chronic condition in which patients suffer troublesome symptoms and/or complications as the reflux of stomach contents occurs.

RefractoryWikipedia

A refractory material or refractory is a material that is resistant to decomposition by heat pressure or chemical attack and retains strength and form at high temperatures. Refractories are polycrystalline polyphase inorganic nonmetallic porous and heterogeneous. They are typically composed of oxides or non oxides like carbides nitrides etc. of the following materials silicon

Celiac diseaseSymptoms and causesMayo Clinic

Refractory celiac disease In rare instances the intestinal injury of celiac disease doesn t respond to a strict gluten-free diet. This is known as refractory celiac disease.

Refractory Generalized Myasthenia Gravis (gMG)

Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fatigable muscle weakness. MG is specifically thought to be an antibody-mediated disease. MG can be treated but a subset of patients remains refractory to conventional therapies leading to refractory generalized myasthenia gravis (gMG).

What is REFRACTORY definition of REFRACTORY (Psychology

Apr 28 2013 · Any disease or disability that resists treatment or fails to react to a prior efficacious therapy. In neurophysiology a neuron or muscle cell which cannot react to stimuli. REFRACTORY "The teenager suffered from refractory acne." Cite this page N. Pam M.S. "REFRACTORY

What is REFRACTORY MENTAL ILLNESS definition of

Apr 28 2013 · REFRACTORY MENTAL ILLNESS. Mental disability or disease which fails to respond to treatment remaining problematic to cure. REFRACTORY MENTAL ILLNESS " Schizophrenia is a refractory mental illness." Cite this page N. Pam M.S. "REFRACTORY MENTAL ILLNESS " in PsychologyDictionary April 28 2013 https //psychologydictionary

Refractory PeriodontitisPeriodontal DiseaseClick to

Dec 17 2020 · The prevalence of these illnesses may be up to 5" " the 111V associated periodontal diseases in- Refractory periodontitis has been defined In the American cademy of Periodontology as "those patients who tire unresponsive to any treatment provided whatever the

Outcomes in refractory diffuse large B-cell lymphoma

Oct 19 2017 · Refractory DLBCL (including subtypes PMBCL and TFL) was defined as progressive disease (received ≥4 cycles of first-line therapy) or stable disease (received 2 cycles of later-line therapy) as best response to chemotherapy or relapse ≤12 months after ASCT.

Outcomes in refractory diffuse large B‐cell lymphoma

Jan 22 2021 · Refractory disease resulted in poor clinical outcomes in DLBCL. However there have been discrepancies in the definition of refractory DLBCL among clinical studies due to different

Definitions of Resistant and Refractory Cytomegalovirus

Definition. Refractory CMV infection Refractory CMV end-organ disease is defined by a worsening in signs and symptoms or progression into end-organ disease after at least 2 weeks of appropriately dosed antiviral therapy (CMV end-organ disease is defined as per Ljungman et al .

What Is Relapsed vs. Refractory Myeloma The Myeloma Crowd

Feb 02 2019 · Dr. Damian Green MD of the Fred Hutchinson Cancer Center generally defines Refractory Myeloma as "disease that is progressing despite active treatment." The National Cancer Institute breaks it down even further to say that there are two main types of refractory myeloma patients 1.

Celiac diseaseSymptoms and causesMayo Clinic

Summarising current Refractory Disease definitions in

Refractory Disease is defined as resistance to multiple drugs with different mechanisms of action by persistency of physical symptoms and high disease activity including contributing factors. A clear unifying definition needs implementing as the plethora of different definitions makes study compari

Managing Refractory Periodontal Disease Using the

Despite the best therapeutic efforts by dental professionals to treat periodontal disease some patients do not respond as well as expected. These cases appear resistant to treatment and as such these patients are deemed to exhibit Refractory Periodontitis. 1 The nature and pathogenesis of Refractory

Refractory Meaning Best 17 Definitions of Refractory

What does refractory mean The definition of refractory is stubborn or hard to manage or heat resistant. (adjective) An example of someone who is

Refractory disease in systemic lupus erythematosus

There is no definition or guidelines for refractory disease (RD) in Systemic Lupus Erythematosus (SLE). However new therapies have been tested mainly in refractory patients. The concept like the disease is complex and implies deeper knowledge on the disease pathogenesis and patients subsets.

What Is Relapsed vs. Refractory Myeloma The Myeloma Crowd

Feb 02 2019 · Dr. Damian Green MD of the Fred Hutchinson Cancer Center generally defines Refractory Myeloma as "disease that is progressing despite active treatment." The National Cancer Institute breaks it down even further to say that there are two main types of refractory

Refractory Celiac DiseaseNORD (National Organization

Refractory celiac disease (RCD) is a complex autoimmune disorder much like the more common celiac disease but unlike celiac disease it is resistant or unresponsive to at least 12 months of treatment with a strict gluten-free diet.