The combined effect of wet granulation process parameters
Sep 01 2016 · The effect of three batch wet granulation process parameters was evaluated using a multivariate experimental design with a novel constrained design space. Batches were characterised for moisture content granule density crushing strength porosity disintegration time and dissolution.
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Challenges in the Development of Pre-filled Syringes for
Other formulation parameters which have been reported to have an influence on tungsten induced protein degradation besides pH are protein concentration and ionic strength 18 . Thus pH protein concentration and ionic strength of a formulation should be taken into account in the risk assessment for tungsten compatibility of a formulation.
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Effects of Formulation Composition on the Characteristics
Objectives To investigate the effects of formulation composition on the physico-chemical and drug release properties of mucoadhesive buccal films prepared by melt extrusion technology using a response surface methodology. Methods Salbutamol sulphate an antiasthmatic drug was used for this study. Klucel hydroxypropylcellulose (HPC) EF (film-forming polymer) Benecel
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Effect of Welding Process Parameters On Tensile Strength
4.1 Direct effect of process parameters on responses 4.1.1 Effects of process parameters on tensile strength (TS) From fig.1 it is observed that TS is directly proportional to S and G and inversely proportional to F and V. The increases in S and G increase the TS whereas the increase in F and V decrease in TS. Fig. 1 Effects of process
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British Library EThOS Effect of formulation parameters on
The main body of this project has been dedicated to investigating the effect of key formulation parameters such as pH ionic strength and temperature on the stability and the aggregation mechanism of a model protein Glucose oxidase at low (1 mg/ml) protein concentration.
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The Influence of Formulation and Manufacturing Process
properties of gelatin by varying formulation parameters to determine their influence on orally disintegrating tablet (ODT) characteristics. Process parameters namely pH and ionic strength of the formulations and ball milling were investigated to observe their effects on
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Effect of Various Formulation Parameters on the Properties
Title Effect of Various Formulation Parameters on the Properties of Hydrogel Wound Dressings VOLUME 2 ISSUE 1 Author(s) Harshalkumar Jadhav Amita Joshi Manju Misra and Aliasgar Shahiwala Affiliation Dubai Pharmacy College P.O.Box 19099 Dubai. Keywords Hydrogel Silver sulfadiazine irradiation cross-linking polyvinyl alcohol polyvinyl pyrrolidone WVTR PVA silver sulfadiazine
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Effect of Some Parameters on the Compressive Strength of
Enhancements in the compressive strength of ordinary Portland cement (OPC) mortar upon the incorporation of multiwalled carbon nanotubes (MWCNTs) were investigated. The MWCNT concentration water/cement (W/C) ratio curing age and MWCNT concentration control method were selected as experimental parameters and their effect on the compressive strength of the MWCNT-cement
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FFECT OF FORMULATION PARAMETERS PON THE STRENGTH
EFFECT OF FORMULATION PARAMETERS UPON THE STRENGTH DEVELOPMENT OF CALCIUM ALUMINATE CEMENT CONTAINING CASTABLES by Christopher PARR Christoph WOEYER Benoît VALDELIEVRE and Akihiko NAMBA Kerneos France 8 rue des graviers 92521 Neuilly sur Seine cedex Presented at the TARJ Refractory Conference Osaka Japan 2002
Get PriceEvaluation of formulation and effects of process
Evaluation of formulation and effects of process parameters on drug release and mechanical properties of tramadol hydrochloride sustained release matrix tablets Nenad D. Nikolić1 Djordje P. Medarević2 Svetlana R. Ibrić2 Zorica R. Djurić2 1Hemofarm a.d. Beogradski drum b.b. Vršac Serbia
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(PDF) Effect of process parameters on the strength of
D critical is the critical size of the nugget required for pull-out failure t the sheet thickness and f a porosity factor to consider influence of nugget porosity on the weld strength.D critical ¼ 3 2t fð3ÞThough the effect of the process parameters on the mechanical behaviour of resistance spot welds on carbon and stainless steels is well
Get PriceFormulation Ex-Vivo and Preclinical In-Vivo Studies of
of conventional formulation containing class I drugs exhibits poor therapeutic effect and bioavailability. So in situ gelling system was formulated and characterized. Methods Box-Behnken design was used to statistically optimize the formulation parameters and evaluate the effects of formulation attributes namely concentration of gellan gum (X 1
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Effect of Laser and Mechanical Parameters on Strength of
The length of the optical fiber which contains the sensor must be able to withstand the tensile loads that will be placed on it during the duration of its service lifetime. It is important to assess the effect of the UV radiation and removal of coating on the strength of the fiber within the region where the grating has been written. In this study we have identified the various mechanical and
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Impact of Formulation and Processing Parameters on
The effect of various formulation and process parameters on the extraction of silicone from siliconized cyclic olefin copolymer (COC) syringes is reported. The impact of proprietary silicone curing process on COC syringe barrels was evaluated with respect to the rate and extent of silicone extraction. Similarly the impact of formulation parameters such as pH ionic species and cosolvents on
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Impact of Formulation and Processing Parameters on
The effect of various formulation and process parameters on the extraction of silicone from siliconized cyclic olefin copolymer (COC) syringes is reported. The impact of proprietary silicone curing process on COC syringe barrels was evaluated with respect to the rate and extent of silicone extraction.
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(PDF) Effect of process parameters on the strength of
D critical is the critical size of the nugget required for pull-out failure t the sheet thickness and f a porosity factor to consider influence of nugget porosity on the weld strength.D critical ¼ 3 2t fð3ÞThough the effect of the process parameters on the mechanical behaviour of resistance spot welds on carbon and stainless steels is well
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Effects of Formulation Composition on the Characteristics
Objectives To investigate the effects of formulation composition on the physico-chemical and drug release properties of mucoadhesive buccal films prepared by melt extrusion technology using a response surface methodology. Methods Salbutamol sulphate an antiasthmatic drug was used for this study. Klucel hydroxypropylcellulose (HPC) EF (film-forming polymer) Benecel
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Effect of process parameters on the adhesion strength in
The present study evaluates the influence of different process parameters on the bond strength by means of a half factorial experimental design. The considered process parameters are the mold temperature at the interface the injection temperature the injection speed the holding pressure and the initial roughness of the thermoplastic part at
Get PriceEffects of geometrical parameters on the strength and
In order to reduce the height of the protrusion on the clinched joint a height-reducing method by compressing the joint was studied in the present work. An investigation of effects of geometrical parameters on the strength and energy absorption of the height-reduced joint was carried out by experimental method. A series of experiments were performed by varying the geometrical parameters
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Effect of Various Formulation Parameters on the Properties
Title Effect of Various Formulation Parameters on the Properties of Hydrogel Wound Dressings VOLUME 2 ISSUE 1 Author(s) Harshalkumar Jadhav Amita Joshi Manju Misra and Aliasgar Shahiwala Affiliation Dubai Pharmacy College P.O.Box 19099 Dubai. Keywords Hydrogel Silver sulfadiazine irradiation cross-linking polyvinyl alcohol polyvinyl pyrrolidone WVTR PVA silver sulfadiazine
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Effect of Some Parameters on the Compressive Strength of
Enhancements in the compressive strength of ordinary Portland cement (OPC) mortar upon the incorporation of multiwalled carbon nanotubes (MWCNTs) were investigated. The MWCNT concentration water/cement (W/C) ratio curing age and MWCNT concentration control method were selected as experimental parameters and their effect on the compressive strength of the MWCNT-cement
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Effect of Formulation and Granulation Processing
Table 2. Formulation of Pull and Push Layers for PPOP Tablets of Model Drug Y (Control Formulation) Effect of composition of the granulating liquid (altering ethanol water ratio) Blends for pull and push layers were prepared using the formulation as displayed in Table 2 followed by a high shear granulation process as described earlier.
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Effects of Composite Formulation on Mechanical Properties
A positive number indicates an increase in the strength as the parameter was changed from a low (−) level to a high ( ) level. A negative number indicates a decrease in the strength as the parameter was changed from a low (−) level to a high ( ) level. Error bars represent the standard error of the effect (dry ± 16.5 MPa wet ± 6.2 MPa). 4.
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The influence of formulation and manufacturing process
Process parameters namely pH and ionic strength of the formulations and ball milling were investigated to observe their effects on excipient characteristics and tablet formation. The properties and characteristics of the formulations and tablets which were investigated included glass transition temperature wettability porosity mechanical
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Table 2. Formulation of Pull and Push Layers for PPOP Tablets of Model Drug Y (Control Formulation) Effect of composition of the granulating liquid (altering ethanol water ratio) Blends for pull and push layers were prepared using the formulation as displayed in Table 2 followed by a high shear granulation process as described earlier.
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Effect of Formulation Parameters on Adhesive Properties of
j.Y. Petit B.Comelli R. Perrin E.Virguin Effect of formulation parameters on adhesive properties of ANSI 118-15 and 118-11 compliant tile adhesive mortars International Journal of Adhesion
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Effect of pressing parameters on the shear strength of
(2013). Effect of pressing parameters on the shear strength of beech specimens bonded with low solvent liquefied wood. Journal of Adhesion Science and Technology Vol. 27 No. 2 pp. .
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Effect of process parameters on the crush strength of
Effect of process parameters on the crush strength of granular fertilizers is described in 8 . Well know process of dolomite treatment with nitric acid 911 and corresponding results are
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Effects of Formulation Composition on the Characteristics
Objectives To investigate the effects of formulation composition on the physico-chemical and drug release properties of mucoadhesive buccal films prepared by melt extrusion technology using a response surface methodology. Methods Salbutamol sulphate an antiasthmatic drug was used for this study. Klucel hydroxypropylcellulose (HPC) EF (film-forming polymer) Benecel
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